rs1799945
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0.100 |
GeneticVariation |
BEFREE |
Mutation H63D in the HFE gene was associated with a higher risk of type 2 DM, but did not appear to confer risk for diabetic chronic complications.
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20097100 |
2011 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
C282Y and H63D are the main mutations related to hereditary hemochromatosis; these mutations have been reported to be associated with increased risk of developing diabetes mellitus type 2 (DM2).
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19876870 |
2009 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
We present data from the largest case-control study of the C282Y and H63D HFE allele frequencies in typical type 2 diabetes mellitus, as defined by an age of onset greater than 30 years and no requirement for insulin in the first year post-diagnosis.
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12783844 |
2003 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
We initiated the present work to determine whether the presence of the HFE C282Y or H63D mutations could be related to the clinical expression of diabetes mellitus type 2.
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15347835 |
2004 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
Our data indicate significant effects of H63D and C282Y on body iron stores and suggest a potential interaction between HFE genotypes and heme iron intake in relation to the risk of type 2 diabetes.
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16306377 |
2005 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
Relations among serum ferritin, C282Y and H63D mutations in the HFE gene and type 2 diabetes mellitus in the Czech population.
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12148086 |
2002 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
We performed an association study to assess the role of the C282Y and H63D mutations in the HFE gene as a risk factor for type 2 diabetes and diabetic nephropathy.
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11423500 |
2001 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
An increased odds ratio for type 2 diabetes mellitus was observed in persons carrying a D allele at the H63D polymorphism compared with those with an H allele (odds ratio (OR) = 1.21, 95% confidence interval (CI): 1.03, 1.41; P = 0.02).
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22908207 |
2012 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
The results do suggest, however, that the H63D mutation may play a role in the pathogenesis of late onset T2DM and in males in this Polish population.
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12601293 |
2003 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
In the present study, we searched for a relationship between C282Y and H63D gene mutations and the development of proliferative diabetic retinopathy in Caucasians with type 2 diabetes.
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14618419 |
2003 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
Data showed no increased frequency of HFE mutations in persons with type 2 diabetes and no association between H63D mutation and NAFLD in the study population.
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27894410 |
2016 |
rs1799945
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0.100 |
GeneticVariation |
BEFREE |
The C282Y and H63D gene mutations were tested in 338 Caucasians with type 2 diabetes: 156 cases with CAD and 182 subjects with no history of CAD.
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15222129 |
2004 |